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Ketamine Therapy in Grand Rapids

Ketamine Infusion Therapy is a breakthrough in Treating Depression, Anxiety & PTSD.

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  • “Ketamine therapy saved my life. I had been put on every medication for depression since I was 11, and nothing worked. About a month into ketamine treatments, I started noticing slight differences—I wasn't hoping a car would hit me. I was able to say that I feel okay today. I did 12 sessions and two maintenance.”

  • Struggling with Depression, Anxiety, or PTSD? Find Hope in Grand Rapids.

    If you’re struggling with depression, anxiety, or PTSD that hasn’t responded to traditional treatments, you’re not alone.

    Find Lasting Relief with Ketamine Therapy at Exponential Health.

    Exponential Health’s Center for Brain and Body Wellness in Grand Rapids, MI offers ketamine infusion therapy – a proven, mood improvement treatment helping people throughout West Michigan break free from treatment-resistant conditions. Led by Dr. Jansen and Dr. Kozfkay, our team provides expert care in a comfortable environment right here in Grand Rapids.

    Unlike traditional antidepressants that take 4-6 weeks to work, ketamine therapy creates real, lasting change. 85% of patients experience rapid mood improvement within 24 hours of their first treatment.

    Schedule Your Consultation
    A person sits on the edge of a bed with head in hands in a dimly lit room, appearing distressed or deep in thought.

    What Is Ketamine Infusion Therapy?

    Ketamine infusion therapy represents one of the most significant breakthroughs in mental health treatment in decades. Originally developed as an anesthetic in 1964, ketamine has been used safely for over 60 years. The World Health Organization designated it as an “essential medicine” due to its exceptional safety profile.

    What researchers discovered in the early 2000s changed everything: ketamine had profound mood-enhancing effects. Yale School of Medicine called it “the greatest breakthrough in psychiatry in over 50 years.”

    How It Works

    Ketamine therapy works differently than traditional antidepressants. Rather than simply adjusting neurotransmitter levels, it promotes neuroplasticity—your brain’s ability to form new neural connections.

    During an infusion, ketamine acts on NMDA receptors, increasing glutamate and stimulating Brain-Derived Neurotrophic Factor (BDNF). This helps repair damaged neural pathways and encourages new, healthier connections.

    Ketamine also acts upon the Default Mode Network (DMN) – brain regions that can become “stuck” in negative thinking patterns. By disrupting these rigid pathways, it creates an opportunity for your brain to establish more adaptive patterns.

    Ketamine Infusion vs. Traditional Antidepressants

    Many patients at our Grand Rapids clinic continue existing medications while receiving ketamine therapy, then work with their psychiatrist to adjust as symptoms improve.

    Ketamine Infusion Therapy

    • Target root causes
    • Relief within hours to days
    • Effects last months
    • Broad neurotransmitter impact
    • Temporary, mild side effects
    • Tend to awaken

    Traditional Antidepressants

    • Target symptoms
    • Take 4-6 weeks to work
    • Must be taken daily
    • Trial-and-error approach
    • Persistent side effects
    • Tend to numb

    Who Can Benefit from Ketamine Therapy?

    At Exponential Health, we specialize in helping individuals who haven't found relief through conventional approaches. Clinical studies show 71% of people with treatment-resistant conditions respond positively to ketamine therapy.
    • Treatment-Resistant Depression – If you’ve tried multiple antidepressants without success, ketamine offers a different approach that addresses root causes
    • Anxiety Disorders – Helps reset neural pathways driving persistent worry, social anxiety, and panic.
    • Post-Traumatic Stress Disorder (PTSD) – Breaks patterns of hypervigilance and helps process trauma differently.
    • Obsessive-Compulsive Disorder (OCD) – Disrupts rigid thought patterns when SSRIs and therapy haven’t been enough.
    • Chronic Pain Conditions – Can provide relief for CRPS, fibromyalgia, and neuropathic pain.

    The ketamine therapy process

    A woman stands in front of a colorful abstract painting on a canvas, smiling and holding paint-stained cloths in an art studio after Ketamine Therapy in Grand Rapids.
  • “After TEN YEARS of anxiety, panic attacks, and depression—it gave me back my personality. I painted my nails, I dyed my hair, I started art projects, I cooked meals. THANK YOU! From the bottom of my heart.”

  • Schedule Your Consultation
    • Initial Consultation

      Meet with one of our doctors to discuss your medical history, symptoms, and treatment goals. We’ll evaluate whether ketamine therapy is right for you and create your personalized plan. The comprehensive assessment is $250.

    • Preparation

      You’ll receive detailed preparation instructions, including fasting requirements. You’ll need to arrange for a driver, as you cannot operate a vehicle for at least 6 hours after treatment.

    • Ketamine Infusion

      Your infusion lasts approximately 40-60 minutes in a comfortable, private setting. We monitor your blood pressure and oxygen levels throughout. You’ll be provided headphones, a sleep mask, and a weighted blanket. Staff monitors you continuously and is available for support.

    • Observation

      After your infusion, you’ll rest for 15-30 minutes while the effects subside. Our team ensures you’re feeling well before you leave with your driver.

    • Follow Up

      Most patients complete an initial series of 6 infusions over 3 weeks (2x per week on alternate days). We’ll assess your progress throughout and develop a personalized maintenance schedule based on your response.

    Why Choose Exponential Health for Ketamine Therapy in Grand Rapids

    Schedule Your Consultation

    Is Ketamine Therapy Safe?

    The simple answer is: Yes — ketamine is extremely safe when administered by trained medical professionals. Ketamine has been used in medical settings for over 60 years with an excellent safety profile. The World Health Organization recognizes it as an “essential medicine” specifically because of its safety and effectiveness.

    When administered in a clinical setting with proper medical supervision—like at Exponential Health—ketamine infusion therapy is very safe. Throughout your treatment at our Grand Rapids clinic, you’re continuously monitored. We track blood pressure, heart rate, and oxygen levels. Our medical staff is present and trained to manage any concerns.

    Most side effects are mild and temporary, resolving within 15 minutes after the infusion ends. Ketamine used therapeutically in controlled doses has low addiction potential—this is completely different from recreational use.

    Frequently asked questions

    Have a different question? Our team would be happy to help, just reach out and someone on our team will help you out!

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    • Do you accept insurance for ketamine therapy?

      Ketamine infusion therapy is a cash-pay service at Exponential Health. In the state of Michigan, Ketamine Infusion therapy is not currently covered  by insurance. Some components, such as the initial evaluation, may be reimbursable depending on your insurance plan. We provide detailed documentation (superbills) that you can submit to your insurance company for potential reimbursement.

      Many patients use Health Savings Accounts (HSA) or Flexible Spending Accounts (FSA) to pay for treatment.

    • How much does ketamine therapy cost in Grand Rapids?

      The initial comprehensive assessment is $250. Treatment costs vary based on your personalized plan and number of sessions recommended. Contact our office at 616-548-6161 for specific pricing details.

    • How do I get started with ketamine therapy at Exponential Health?

      Call us at 616-548-6161 or schedule your consultation. You’ll begin with a comprehensive assessment to determine if ketamine therapy is right for you and create your personalized treatment plan.

    • Can I drive myself to ketamine therapy appointments?

      No, you cannot drive yourself. Ketamine temporarily affects coordination and judgment. You must arrange for someone to drive you to and from each treatment. You should not drive or operate machinery for at least 6 hours after your infusion.

    • How quickly will I feel results from ketamine therapy?

      Most patients complete an initial series of 6 infusions over 3 weeks (twice per week on alternate days). After your series, we’ll determine your personalized maintenance schedule based on your response. Some patients need monthly maintenance, others less frequently. View pricing.

    • What if I don’t respond to ketamine therapy?

      While ketamine has a 71% response rate for treatment-resistant depression, not everyone responds. If you don’t experience improvement, we’ll explore alternative approaches. Ketamine is part of our comprehensive Center for Brain and Body Wellness, which includes other advanced therapies like vagus nerve stimulation and stellate ganglion blocks.

    • How many ketamine sessions will I need?

      Treatment plans are individualized. Many patients begin with a series of sessions close together, then taper to maintenance as symptoms improve. Typical cadence is six session over three weeks.

    Visit Us

    Grand Rapids, MI – Cascade Rd: 5005 Cascade Rd SE, Suite B Grand Rapids, MI 49546
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    Ready to Start Your Healing Journey in Grand Rapids?

    You don't have to carry the weight of depression, anxiety, PTSD, or chronic pain alone. Ketamine infusion therapy offers new hope, and it's available right here in Grand Rapids. At Exponential Health's Center for Brain and Body Wellness, our compassionate team is here to guide you every step of the way.